Medications & Sensitive Mouth

Dry, Burning, or Just Off? It Could Be Your Meds

Many people experience changes in their mouth — dryness, burning, soreness — without realizing their medications could be the cause.

What Medications Can Trigger Sensitivity?

• Antidepressants and anti-anxiety medications

• Blood pressure medications (especially ACE inhibitors)

• Allergy medications and antihistamines

• Diuretics

• Certain chemotherapy agents

These drugs can affect saliva flow, change oral tissue response, or create imbalance in the mouth’s natural defenses — all of which can lead to discomfort.

Tips to Manage Mouth Sensitivity While on Medication

• Sip water throughout the day (even small sips help)

• Use saliva-boosting products (like xylitol mints or sprays)

• Avoid alcohol-based mouthwashes

• Choose fluoride toothpaste that’s gentle and non-foaming

• Keep a humidifier in your bedroom to support overnight hydration

When to Talk to Your Doctor or Dentist

If your mouth feels unusually dry or sore, or your sense of taste changes, it’s worth checking with your provider. They may recommend dosage changes or simple lifestyle adjustments.